Effect of D-chiro-inositol on hormonal parameters and insulin resistance in women with polycystic ovary syndrome

Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder among women of reproductive age, characterized by hormonal imbalance and insulin resistance. D-chiro-inositol, a naturally occurring inositol isomer, has been suggested as potential treatment option for PCOS. This study aimed to investigate the effects D-chiro-inositol supplementation on parameters, resistance in with Methods: randomized controlled was conducted 60 PCOS resistance, who were assigned either Group A (D-chiro-inositol) or B (placebo) 12 weeks. S. FSH, LH, total testosterone, fasting blood glucose, insulin, (HOMA-IR) measured at baseline after weeks treatment. Statistical analyses performed using SPSS version 23.0 Windows. Results: After treatment, significant reductions serum luteinizing hormone, HOMA-IR observed group compared placebo group. However, no changes glucose levels. well-tolerated, differences side between two groups. Conclusions: significantly improved The suggesting that can be effective therapeutic patients